George was educated at Windermere College and at Trinity College, Dublin, where he graduated B.A. in 1887, and M.B., B.Ch., B.A.O. in 1889. He gained a commission in the Medical Services at the rank of Surgeon-Captain on the 28th July 1891, then served on the North-West Frontier of India, in the Tirah Campaign from 1897 to 1898, receiving the Frontier medal with two clasps for his service there. He received promotion to the rank of Major on 28th July 1903. On 20th January 1913 he was appointed Deputy Assistant Director-General, Army Medical Service at the War Office to direct the branch dealing with questions of hospital equipment, medical & surgical supplies, medical boards, professional matters and voluntary aid, gaining promotion to Lieutenant-Colonel on 13th September 1913. On 28th February 1917, he was appointed Assistant Director-General of the Army Medical Services, but continued in charge of the medical and surgical supply branch until March 1918, when he was appointed Deputy Director-General of the Medical Services - a post he continued until he retired on 16th September 1922. During this time he was promoted to Colonel on 26th December 1917, and again to Major-General in 1918. He was appointed Companion Order of St Michael and St George in 1917; Companion Order of the Bath in 1918; and Knight Commander Order of the British Empire in 1922., and was a member of the British Medical Association for over 50 years. George was the son of Dr. Richard Stanistreet.